Abstract
Since the introduction of CT-based simulation for use in whole brain radiotherapy (WBRT), we have observed that a large volume of the parotid glands is included in the radiation fields. The purpose of this study is to analyze the dose–volume statistics of the parotid glands in patients undergoing WBRT.Thirty-two patients received WBRT using CT-based simulation with bilateral two-field arrangement. Daily fraction was 3 Gy with total dose of 30 Gy in 2 weeks. We analyzed the radiation dose from WBRT to the parotid glands.Average of the mean parotid dose was 17.5 Gy (range, 10.5–26.2) for both glands. Mean parotid doses ⩾20 and ⩾25 Gy were observed in 22 (34.4%) and 4 (6.3%) of 64 individual glands. The numbers of patients with a mean parotid dose of both glands ⩾20 Gy and ⩾25 Gy were 12 (37.5%) and 1 (3.1%), respectively.Mean parotid dose was variable in patients with WBRT. According to the parotid dose and combined potential risk factors, parotid glands can be regarded as a risk organ in WBRT for improvement of patient quality of life.
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