Abstract

Background: Procedural sedation for magnetic resonance imaging (MRI) is frequently required in children to achieve cooperation and immobility for high-quality imaging. Many institutions use propofol infusions alone or in combination with other sedative drugs such as midazolam for sedation during MRI. There are wide ranges of propofol infusion rates reported in the literature (3-18mg/kg/hr) but few details have been reported about the effects of adjunctive midazolam on the dosing of propofol. The practice of our intensivist-led pediatric sedation team for children undergoing MRI typically includes 0.025-0.1mg/kg intravenous (IV) midazolam …

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