Abstract

Conflicting evidence exists surrounding the risk of preeclampsia after assisted reproductive technology (ART). It has been hypothesized that elevated circulating estrogen levels after ovarian stimulation (OS) associated with ART contribute to abnormal placentation, increasing the risk of preeclampsia. We compared the risk of preeclampsia among spontaneous conception deliveries with that among deliveries after OS with ART, OS without ART, OS with only aromatase inhibitors which do not cause supraphysiologic estrogen levels, and unstimulated intrauterine insemination (IUI).

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