Abstract
Long term prognosis was evaluated in 250 consecutive pts (age 62 ± 12 years, 70% male) who developed creatinine kinase (CK) elevation following elective coronary artery interventions (balloon PTCA, directional coronary atherectomy, TEC atherectomy, and excimer laser). CK levels were obtained in all pts every 6 hours for at least 24 hours after PTCA. Median follow up was 2.5 yrs. (0.8, 43) and was obtained in 211 (85%) pts. Cardiac death occurred in 26/211 (12%) pts at 1.2 ± 1.3 years after intervention (range 0.0–4.0 years). Univariate predictors of cardiac death include peak total CK (p < 0.0008), age (p < 0.01), prior coronary artery bypass surgery (p < 0.04), and Q wave myocardial infarction after PTCA (p < 0.04). There were no differences in cardiac death rates between devices. Multivariate predictors of cardiac death were peak total CK (p < 0.0004) and age (p < 0.01). Actuarial survival was related to the degree of CK elevation as shown below:Download : Download high-res image (85KB)Download : Download full-size image CK elevation following elective PTCA is associated with an increased risk of cardiac death at long term follow up. The degree of CK elevation and age are independent predictors of late cardiac death.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
