Abstract
regression. RESULTS: 10,705 VLBW: 3846(1995-2000), 3475 (2001-2005), 3384 (2006-2010):total neonatal mortality decreased significantly (p 0.0001) : OR 1; 0.78 ( 0.67-0.90); 0.72 (0.62-0.84) respectively. The significant lower threshold of this improvement pattern was BW 500 & GA 25wks, and lost significance 31 weeks. All severe morbidities decreased significantly (Table). A significant increase in maternal age (p 0.0001),high education ( 13 y) p 0.0001, antenatal care started 12 weeks (72.6% women to 82.0%) (p 0.0001) and fertility therapy (p 0.0003) occured. Hypertension and antepartum bleeding showed no change, while GDM increased (p 0.005). Interestingly, significant decrease in premature labor (p 0.0001), PPROM (p 0.0001) and chorioamnionitis (p 0.0001) observed. The cesarean raised significantly (60.8% to 67.9%) (P 0.0001); with no significant change in GA at birth (28.3 / 2.3) and its distribution, BW, gender and SGA. However, there was a significant decrease in delivery room resuscitation (p 0.0001) and 5’Apgar 7 (p 0.0006). CONCLUSION: The comparison of VLBW infants outcomes born five years apart showed a significant decrease of mortality and morbidity, paralleled by noteworthy changes in the maternal demographic characteristics. This analysis emphasizes the need to continuously follow and update neonatal outcomes. The provision of an appropriate estimate of neonatal risks is mandatory in counseling families.
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