Abstract
After severe injury, adult mammalian wound healing occurs by formation of fibrotic scar and loss of skin appendages resulting in permanent functional impairment. In mice, severe skin injuries exhibit partial regeneration, including formation of new hair follicles (HFs) in the center of the wound, whereas the periphery remains fibrotic. We previously showed that fibroblasts residing within the regenerative zone exhibit activation of unique transcriptional programs reminiscent of early skin development (Abassi et al, Cell Stem Cell).
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.