751 Temporal Trends in Hospitalisation Rates of Males and Females following Acute Pulmonary Embolism in New South Wales, Australia: A 17-Year Population-Linkage Study

Abstract

No previous Australian study has compared the temporal trend in pulmonary embolism (PE) hospitalisation rates between gender. Retrospective population-linkage study of all New South Wales (NSW) residents admitted with a primary diagnosis of PE between January-1, 2002 and Deccember-31, 2018 using data from The Centre-for-Health-Record-Linkage database, which encompasses >97% of all healthcare facilities state-wide. The size of NSW population during corresponding study time-period was obtained from the Australia Bureau of Statistics public data. Over 17-years, there were 61607 admissions for acute PE, with a mean admission case-rate of 50.42±3.70 admissions-per-100,000-persons-per-annum. Females had a higher total number of admissions over the study period (34329 vs 27278 admissions respectively). The mean admission case-rate-per-annum was higher for females than males (54.85±3.65 vs 44.91±4.34 admissions-per-100,000-persons-per-annum respectively). Females reached a maximum admission-case-rate of 60.5 admissions-per-100,000-persons-per-annum in 2013 and a minimum of 47.7 admissions-per-100,000-persons-per-annum in 2006. Males reached a maximum 50.7 admissions-per-100,000-persons-per-annum in 2017 and a minimum of 37.3 admissions-per-100,000-persons-per-annum in 2004. The admission case-rate per-100,000-persons remained relatively stable for both males and females throughout the study period. When limited to index PE admission for patients who had recurrent PE presentations during the study period, the mean admission rate was 40.68±2.31 persons-per-100,000-persons-per-annum. This figure remained relatively stable throughout the study period, suggesting that hospitalisation rates for recurrent PE have also remained stable over time. The total PE case number and mean admission case-rate per 100,000-persons was substantially higher for women than men and remained stable over the 17-year study period.