Abstract

In the title compound, C29H20F3NO3S, the thia­zolidine ringadopts a half-chair conformation. The pyrrolidine and two five-membered carbocyclic rings are in envelope conformations with the spiro C atoms at the flaps. The trifluoro­methyl-substituted benzene ring forms dihedral angles of 62.37 (14) and 87.40 (14)° with the benzene rings of the dihydro-1H-indene units. The two benzene rings form a dihedral angle of 36.94 (15)°. The mol­ecular structure is stabilized by intra­molecular C—H⋯O hydrogen bonds, which generate S(6) ring motifs. In the crystal, mol­ecules are linked into inversion dimers by pairs of inter­molecular C—H⋯O hydrogen bonds, generating R 2 2(10) ring motifs.

Highlights

  • In the title compound, C29H20F3NO3S, the thiazolidine ringadopts a half-chair conformation

  • The pyrrolidine and two five-membered carbocyclic rings are in envelope conformations with the spiro C atoms at the flaps

  • The molecular structure is stabilized by intramolecular C—H O hydrogen bonds, which generate S(6) ring motifs

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Summary

Structure Reports

70 -[4-(Trifluoromethyl)phenyl]50 ,60 ,70 ,7a’-tetrahydrodispiro[indan-2,50 pyrrolo[1,2-c][1,3]thiazole-60 ,20 0 -indan]1,3,10 0 -trione. USM, Penang, Malaysia, and bX-ray Crystallography Unit, School of Physics, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia. R factor = 0.063; wR factor = 0.216; data-to-parameter ratio = 20.7. C29H20F3NO3S, the thiazolidine ringadopts a half-chair conformation. The pyrrolidine and two five-membered carbocyclic rings are in envelope conformations with the spiro C atoms at the flaps. The trifluoromethyl-substituted benzene ring forms dihedral angles of. 62.37 (14) and 87.40 (14) with the benzene rings of the dihydro-1H-indene units. The two benzene rings form a dihedral angle of 36.94 (15). The molecular structure is stabilized by intramolecular C—H O hydrogen bonds, which generate S(6) ring motifs. Molecules are linked into inversion dimers by pairs of intermolecular C—. H O hydrogen bonds, generating R22(10) ring motifs

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The authors thank Pharmacogenetic and Novel Therapeutic
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