Abstract
Introduction Vitamin D is a fat-soluble steroid hormone, which can be converted into various forms, which are extremely physiologically important for our body. However it has not yet been well studied its functions and local metabolic pathways in some organs, such as eye. Purpose To verify the correlation between vitamin D levels in blood and tear and the possibility of using tear as a biological material for monitoring eye disorders in the future. Methods An electrochemiluminescence method was used to examine the blood and tear samples, which was collected with a Schirmer test strip from 21 individuals without ocular disease. Results At the 95% confidence interval, tear vitamin’s mean = 37.8 ± 3.6ng / mL, which is higher than the serum level, which presents a mean of 30.3 ± 7.7ng / mL; The coefficient of correlation of Lin = –0.018 (–0.174; 0.139), Pearson coefficient = –0.070 and the Bland-Altman coefficient = –11.12 (–30.40; 8.16). Results obtained by the program Stata version 11.0. Conclusions It is possible to determine levels of vitamin D in the tear using the electrochemiluminescence method and as the results with the blood do not correlate, there is possibility of using the tear as a biological matrix for detection of vitamin D may increase the possibilities of new studies in eye disorders.
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