738 Quantification of mechanical dyssynchrony and non-uniform left ventricular mechanical function by conductance catheter in heart failure patients

Abstract

from rats fed a diet containing alcohol, rates of protein synthesis were assessed in vivo. The global rate of protein synthesis was reduced by 30% (P<0.05) in hearts from animals consuming alcohol compared with pair-fed controls. We conclude that defects in protein metabolism in animals consuming a diet containing alcohol may contribute to reduced LV function through changes in the mass of the ventricle. (Suppored by NIH grant NIAAA12814)