736: Angiogenic biomarkers for the prediction of pregnancy complications in women with suspected preeclampsia

Abstract

cluded: death, RDS, grades 3 or 4 IVH, sepsis, NEC, or retinopathy of prematurity. The primary composite maternal outcome included: death, pulmonary edema, blood transfusion, ARDS, CVA, ATN, DIC, or liver rupture. RESULTS: Of 9960 evaluated pregnancies, 114 delivered 20 weeks and 101 had major fetal birth defects. Overall 28.2% had PAH 19.2% mild GTHN, 2.0% severe GHTN, 3.8% mild PrE, and 3.1% severe PrE. Outcome risks by PAH type (all p-values 0.001) and adjusted ORs (with no PAH as referent) are given (Table). Maternal and perinatal outcomes were elevated the most for severe PrE (2.6 to 9-fold) and least for mild GHTN (0.7 to 2.4-fold). CONCLUSION: The risks of adverse outcomes increase with severity of PAH sub-type. Mild PrE has similar perinatal risks to severe GHTN but maternal risks are greater.