Abstract
INTRODUCTION: To assess the association between neutrophil to lymphocyte ratio (NLR), lymphocyte to monocyte ratio (LMR) and neutrophil to monocyte ratio (NMR) in adults 20-70 years old with inflammatory bowel disease (IBD) using a nationally representative database of the United States population. METHODS: Analysis was performed on 4,739 persons aged 20-70 years from the 2009-2010 National Health and Nutrition Examination Survey (NHANES) who responded to the question “has a doctor or health professional ever told you that you have ulcerative colitis or crohns disease. Participants with a diagnosis of cancer were excluded in the analysis. Mean values of neutrophils (N), lymphocytes (L), monocytes (M) and their ratios were compared between groups of participants with and without inflammatory bowel disease. RESULTS: There was no significant difference in NLR and LMR between participants with and without inflammatory bowel disease. Compared with participants without IBD, participants with IBD had a higher NMR (7.95 95%CI: 7.80, 8.09 vs 8.84, 95% CI: 7.91, 9.76). CONCLUSION: A high NMR might be effective, readily available and low-cost biomarker for assessment of people with inflammatory bowel disease. Further studies are needed to clarify the difference in NMR between people with and without IBD.
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