Abstract
Advancing insights into QOL of long-term survivorsIn this presentation, the following topics will be addressed: •Changes in health related quality of life over time from time of diagnosis to 2 years after treatment•Health related quality of life in relation to survival•What is the role of personal, clinical, biological, physical, psychological, social, lifestyle, and HNC-related factors?Data was used of The NETherlands QUality of life and BIomedical Cohort study in head and neck cancer (HNC) (NET-QUBIC) a prospective cohort study including 739 HNC patients and 262 informal caregivers. NET-QUBIC comprises a Data Warehouse and Biobank integrating detailed clinical information and data derived from patient reported outcomes, interviews, and functional tests, and samples of tumour tissue, blood, oral rinse, and saliva. Data and samples are available to researchers worldwide via data releases that are announced on www.kubusproject.nl.In the present study, we used NET-QUBIC data and samples to investigate the course of health related quality of life of HNC patients from diagnosis to 3, 6, 12 and 24 months after treatment. Health related quality of life was operationalised by the EORTC QLQ-C30 global quality of life subscale (2 items) and the summary score.
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