Abstract
Our previous maximal exercise studies performed on patients with left ventricular volume or pressure overload or cyanotic lesions revealed decreases of heart rate(HR), systolic blood pressure(BP), workload(Wmax), and peak working capacity index(PWCI)in comparison to 405 healthy controls. We sought to define these data in children with ASD (n=35) or VSD (n=79). The data were compared by analysis of covariance, controlling for age, sex, race, and body surface area.Age and body surface area were significant covariates for the BP, Wmax, and PWCI variables. There were strong main effects of race on HR and BP values, and both race and sex on the 2 workload indices. The ASD and VSD patients had decreased values of maximal HR; the ASD patients had low values of PWCI. As in almost all other patient groups, the BP response to exercise for ASD or VSD patients did not differ from control. Racial influences on BP were significant; in each comparison, the black children had higher values than their white counterparts.
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