Abstract
Introduction: Pulsatile vascular compression of the ventro-lateral medulla has been implicated as the etiology of neurogenic essential hypertension. While the neural network involved in vasomotor control has been well studied in animals, it has not been physiologically determined in humans. A more detailed knowledge of the exact anatomy and physiologic function of this area of the medullary surface would further aid in studies regarding neurogenic hypertension. MethodS: We used bipolar electrode stimulation and recorded blood pressure responses in order to exactly identify the so called vasomotor center in the human medulla. This mapping of the medullary surface was done in patients undergoing posterior fossa surgery. We will present our findings from 15 patients. Results: A side difference in the response to stimulation was realized. In addition, we have found that stimulation of the mid- to inferior retro-olivary sulcus produces a hypertensive response, while stimulation of an area slightly caudal to...
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