Abstract
Stomatitis-related oropharyngeal pain contributes to morbidity in hematopoietic stem cell transplantation (HSCT) patients. We report results of a pilot study for a stomatitis intervention trial including effectiveness of opioids to manage oropharyngeal pain, and laboratory techniques to measure concentrations in plasma and salivary cell pellets. Multiple dimensions of pain were assessed pre- and 9 days post conditioning chemotherapy (CT) regimens using the Oral Mucositis Assessment Scale and Painometer.” Plasma concentrations were measured (N = 23) using ELISA (ELISA; R&D Systems, Inc., Minneapolis, MN).
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