71 Heparin May Not Be Needed as a Transition to Long Term Warfarin Therapy in LVAD Destination Therapy Patients

Abstract

0.8). Eight ChC pts exhibited Ra (34.7%): 6 had skin lesions, 1 had parasitemia and 1 had Chagas myocarditis; 1 pt had Ch myocarditis relapsed. The mean Ra time was 75 days (d) (range 38-120); 1 pts showed a positive Strout result 15 d before the Ra; positive results were observed in the rest of the pts when the clinical lesion was detected. k-DNA and SL-DNA PCR were positive 50 d and 36 d before Ra. The use of MMF was no related to Ra episodes: 2/8 pts in Ra group vs 6/15 pts in non Ra group. (p:0.47). All the Ra were successfully treated with BNZ. The incidence of CAV was 12.4% in GI and 12.5% in G2. Survival at 1, 3 and 5 years was 82%, 82% and 68% for G1 and 80%, 75% and 71% in G2 (log rank test p0.7). Conclusions: Ra was observed in 34.7% in chagasic recipients, treatment with BNZ was successful and any pts died because of Ra. The incidence of CAV and the survival results after HTx are similar between chagasic and no chagasic recipients. This confirms that HTx is a valuable treatment option in ChC.