Abstract

Anti PD-1/PDL-1 immune check point inhibitors (ICI) had dramatically changed the survival of patients with advanced non-small cell lung cancer (NSCLC). After platinum-based chemotherapy and ICI failure, taxane regimen remains standard of care. Some data have suggested an increased activity to chemotherapy received after ICI. Nevertheless, taxane appears to have modest effectiveness in pre-treated patients. We aimed to assess survival outcomes with taxane chemotherapies after ICI exposure and to identify prognostic and predictive factors that may influence response to those regimen.

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