Abstract
VEGF −634 GG and GC genotypes as well as +936 CT and TT genotypes are significantly associated with higher levels of VEGF (p =0.01 and 0.000, respectively). A significant positive correlation was observed between serum VEGF and tumor size (r = 0.573, p =0.000), multiple tumor masses (r = 0.564, p =0.004), and AFP (r = 0.623, p =0.000). Conclusion: Serum VEGF and both +936 and −634 gene polymorphisms have the potential to be useful biomarkers for prognosis of HCC Egyptian patients.
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