Abstract
PurposeHere we describe our first experience with contrast-enhanced (CE) MRI of breast cancer at 7tesla (T), compared to 3T and histopathology. Materials and MethodsA 52 year old female patient with a mammographically suspicious breast mass (BI-RADS V) underwent 7T CE-MRI. Results were described according to the BI-RADS-MRI criteria and compared to 3T and histopathology. ResultsAfter contrast administration, a homogeneously enhancing, irregular spiculated mass was depicted at both 3T and 7T; sizes were identical. The most malignant kinetic curve was characterized by a rapid initial rise followed by a wash-out pattern in the delayed phase, i.e. a type 3 curve, at both field strengths. Even though T1-effects of contrast agents are suggested to be reduced at higher fields, quantification of contrast enhancement-to-noise ratio showed a ratio of 4.6 at 7T and 2.8 at 3T when comparing contrast-to-noise of the mass before and after contrast administration. Both examinations, using a single dose of gadolinium-based contrast agent, achieved good image quality. Final histopathological evaluation showed an invasive ductulolobular carcinoma with an intraductal component. ConclusionThis initial experience suggests that clinical contrast-enhanced 7T MRI of the breast is technically feasible and may allow BI-RADS-conform analysis.
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