Abstract

7 Highly polar, water-soluble prodrugs of the HIV protease inhibitor amprenavir: A new approach toward a more compact dosing regimen : A. Spaltenstein 1, C. Baker 2, Y. Graynunez 1, I. Kaldor 1, W. Kazmierski 1, D. Reynolds 1, R. Tung 2, P. Wheelan 1, E. Furfine 1 1Glaxo Wellcome Inc., Res. Triangle Park, NC, USA and 2Vertex Pharmaceuticals, Cambridge,

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