7. Complications of Ovarian Tissue Cryopreservation in Adolescent Patients Undergoing Bone Marrow Transplant

Abstract

Myeloablative therapy prior to bone marrow transplant (BMT) can cause irreversible primordial follicle damage and premature ovarian insufficiency (POI). One option for fertility preservation in young patients is ovarian tissue cryopreservation (OTC). There is limited literature on the possible impact on ovarian reserve, death, and complications following OTC. We hypothesize that patients undergoing OTC and BMT will have no difference in complications compared to those who have undergone BMT alone.