Abstract

In the title compound, C34H35NO4, the dihedral angle between the pyridine ring and attached benzene ring is 79.17 (8)°. The methoxyethoxy–ethoxy side chain is disordered over two orientations in a 0.732 (7):0.268 (7) ratio. In the crystal, very weak C—H...N and C—H...O interactions link the molecules.

Highlights

  • In the title compound, C34H35NO4, the dihedral angle between the pyridine ring and attached benzene ring is 79.17 (8)

  • The methoxyethoxy–ethoxy side chain is disordered over two orientations in a 0.732 (7):0.268 (7) ratio

  • An ether oxygen chain was introduced into the title compound in an attempt to improve its solublity

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Summary

Structure description

Ethyl vanillin derivatives have various biological properties (Sainsbury et al 2013) but many of them show poor lipid solubility (Wu et al 2018). An ether oxygen chain was introduced into the title compound in an attempt to improve its solublity. In the crystal structure (Fig. 1), the dihedral angle between the pyridine ring and adjacent benzene ring is 79.17 (8). The methoxyethoxy-ethoxy side chain is disordered over two orientations in a 0.732 (7):0.268 (7) ratio. Very weak C29— H29Á Á ÁO4 (2.69 A ) and C27—H27Á Á ÁN1 (2.67 A ) interactions (Table 1, Fig. 2) occur (Wang et al 2019)

Synthesis and crystallization
No of restraints
Crystal data
Bruker APEXII CCD area detector diffractometer
Special details
Full Text
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