Abstract
This chapter describes the different natural enzymes that have been discovered that can specifically halogenate organic compounds and that have applications in biotransformation reactions. Specific halogenation of a compound can change its chemical and biological properties. There are many naturally halogenated compounds that have been isolated from both marine and terrestrial environments and some examples are presented. Many of these compounds have properties that are of interest to the pharmaceutical industry since they have antibacterial or anticancer activities. This chapter summarizes the enzymes discovered to date and discusses their properties. They include heme haloperoxidases, nonheme iron-dependent halogenases, vanadium haloperoxidases, flavin-dependent haloperoxidases, noncofactor-containing bacterial haloperoxidases, S-adenosyl-l-methionine-dependent chlorinases and fluorinases, and methyl halide transferases. These enzymes are unrelated structurally and use different mechanisms to achieve their chemical reactions. The known applications of well-studied enzymes are discussed alongside potential applications of more recently discovered enzymes for white biotechnology.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
