Abstract
In this study, we investigated the antioxidant activities and compared other physiological properties including anti-cancer and antimicrobial effects of several traditional Korean herb-combined remedies such as Gilgyung-tang (GGT), Daihwangmokdan-tang (DHMDT), Sagan-tang (SGT), Socheonryong- tang (SCRT), Sihocheonggan-tang (SHCGT), Sipyukmiyuki-eum (SYMYKE) and Hwangheuk-san (HHS), which were recorded in Dong-eui-bo-gam for Ongjeo. Total phenolic contents of the herb medi- cines were in a rich order of GGT < SYMYKE < SCRT < SHCGT < DHM DT < SGT < HHS. Among them, HHS appeared highest in superoxide dismutase-like activit y, ferric reducing antioxidant power, scavenging of 2,2'-diphenyl-1-picrylhydrazyl, and 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonate) cati- onic radical activity. Interestingly, there was a positive rela tionship between their total phenolic con- tents and their antioxidant activities. Although all of them showed anti-proliferative activities in hu- man colon cancer HCT-116 cells, HHS was seven times higher than GGT. Antimicrobial activities against Escherichia coli and Helicobacter pylori were revealed only on SGT, SCRT, SYMYKE and HHS. Taken together, these findings reveal the potential use of traditional Korean herbal formulas as func- tional ingredients in antioxidant and physiological materials.
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