Abstract

Contribution to the International Chain Elongation Conference 2020 | ICEC 2020. An abstract can be found in the right column.

Highlights

  • To increase the product portfolio of microbial chain elongation, we are developing a stable bioprocess system with membrane-based liquidliquid extraction to include n-caprylic acid (C8; n-octanoic acid) in addition to other medium-chain carboxylic acids (MCCAs) such as n-caproic acid (C6; n-hexanoic acid) and n-heptanoic acid (C7)

  • We investigated whether we could repeat this result from Cornell University with a stable production of a considerably higher amount of C8 than C6 when a mixture of ethanol and acetate was fed as substrate

  • RESULTS & DISCUSSION: The C8-producing anaerobic filter (AF) was filled with K1-filter media (Kaldnes) in a 5

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Summary

Introduction

To increase the product portfolio of microbial chain elongation, we are developing a stable bioprocess system with membrane-based liquidliquid extraction (pertraction) to include n-caprylic acid (C8; n-octanoic acid) in addition to other medium-chain carboxylic acids (MCCAs) such as n-caproic acid (C6; n-hexanoic acid) and n-heptanoic acid (C7). This had been accomplished with a relatively small wet volume of 0.7 L. We scaled up the process 6x to a 4.2-L wet volume AF. We investigated whether we could repeat this result from Cornell University with a stable production of a considerably higher amount of C8 than C6 when a mixture of ethanol and acetate was fed as substrate.

Results
Conclusion
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