Abstract

Purpose: The application of tumor tracking techniques for intra-fraction motion compensation in particle radiation therapy is challenging due to the need to account both for target motion and for particle range fluctuations induced by tissue density variations along the beam line. The aim of this work is to develop and investigate a tumor tracking method for an application in particle therapy, providing the daily respiratory dynamics of the entire patient anatomy as a function of an external surface surrogate combined with an a priori motion model.

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