69 Impact of DON in a Protocol of Calcium Depletion and Repletion in Piglets

Abstract

Abstract This study aimed to evaluate factors that modulate phosphorus (P) use, such as calcium (Ca) intake that is well known and deoxynivalenol (DON) contamination which has been the subject of few studies until now. A total of 64 piglets (2 piglets per pen) received 1 of 4 treatments distributed into 8 blocks during an initial 13-d phase: control (DON-) or DON-contaminated treatment (DON+, 2.72 mg/kg) with either a low Ca (Ca-, 0.39%) or normal Ca (Ca+, 0.65%) level with a constant digestible P level (0.40%). During a second 14-d phase, piglets that received Ca+ and Ca- were fed a similar diet containing 0.65% Ca and 0.35% P without DON contamination. Growth performance and apparent total tract digestibility (ATTD) of Ca and P for piglets and bone mineral content (BMC) of 1 pig per pen were evaluated. After phase 1, ATTD P was higher for Ca-DON+ (DON x Ca interaction, P < 0.01). The ATTD Ca was higher for DON+ (( P < 0.001). The DON+ increased BMC in Ca+ but opposite effect was observed in Ca- (DON x Ca interaction, P < 0.001). The plasma P concentration was greater for Ca- (P = 0.05). After phase 2, average daily gain (P = 0.08) and average daily feed intake (P = 0.09) tended to be less for Ca- than for Ca+. The Ca- piglets recovered their BMC deficit in DON-, but not those receiving DON+ (DON x Ca interaction, P = 0.06). ATTP P in DON- was lower in Ca+ but increased in DON+ regardless of Ca level (DON x Ca interaction, P = 0.04). Plasma P and Mg were greater for Ca- (P = 0.05). The results show that piglets can regain the BMC caused by Ca depletion in DON non-contaminated feed. DON contamination increased Ca and P digestibility and modified BMC depending on Ca supply.