677 Positive correlation between thermal sensitivity and trans-epidermal water loss on healthy human skin

Abstract

Cutaneous thermal sensitivity is very important and has been studied extensively. Thermal sensitivity is known to change by various conditions, such as inflammation and chemicals in in vitro. Surroundings, age, and individual body parts are additional factors that cause thermal sensitivity to change in in vivo. However, there are few reports mentioning the relationship between thermal sensitivity and skin condition states. In order to clarify their relationship, two studies were conducted. Firstly, the difference in thermal sensitivity according to various differing skin condition states was examined. Secondly, the same test was conducted to compare healthy sites and inflamed sites.Thermal sensitivity and physiological parameters of cheek were measured in 303 subjects (20s-50s, females). Subjects were grouped by thermal sensitivity, and trans-epidermal water loss (TEWL) of high thermal sensitivity group was high, and the TEWL of low group was low. Further, in a questionnaire conducted on the test subjects, high thermal sensitivity group had a higher degree of self-reported dry skin, and also, low group had a lower degree.