Abstract
The stratum corneum (SC) of the skin is thicker in areas with pigmented spots than in areas without pigmented spots. Despite this difference in SC characteristics, the physical properties of skin with pigmented spots have not yet been studied. We compared skin hardness and measured the amount of desmoglein 1 (Dsg1) in the SC at sites with and without pigmented spots. Since cell adhesion proteins can increase SC thickness, we assumed that the physical properties of the SC are also associated with cell-cell adhesion.
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