Abstract

Dalbavancin is a lipoglycopeptide antibiotic with activity against Grampositive pathogens and a long half-life allowing for weekly dosing. DISCOVER 1 and 2 were identically designed clinical trials of dalbavancin versus vancomycin (VAN) with option to switch to oral linezolid for the treatment of ABSSSI. We evaluated outcomes of ABSSSI in patients treated with VAN by dosing regimen utilized and serum trough concentrations for VAN.

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