Abstract
The initial curative standard therapy for LAHNSCC by exclusive CRT or surgery (+/- CRT) have similar results in term of PFS and OS. Indication depends on several factors including regional expertise and anticipated sequela. The role of induction chemotherapy (IC) remains questionable until today. Previous publications suggested that surgery followed by CRT could be relevant for high-risk relapse tumors. The aim of this retrospective study was to compare as first-intent curative treatment CRT to alternative approach (S/IC: surgery and/or IC +/- CRT).
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