Abstract
The light distribution in vivo during Photodynamic Therapy is dependent on a pre-administered photosensitizer in the target tissue. To discuss the light absorption of photosensitizer (ME2906), the light distribution in normal muscle at 664nm was measured with optical detector fiber. From this distribution, the absorption coefficient of ME2906 in tissue was calculated. As an optical source, a semiconductor laser is prepared. The incident laser beam diameter at the tissue surface is 10mm, and the power density was 100mW/cm2. In proportion as the concentration of ME2906 increases, absorption coefficient of ME2906 increases in the range from 0.06 to 0.16mm-1. This coefficients are related to ME2906 concentrations in the plasma and tissue. Therefore, ME2906 concentrations of plasma were examined by high-performance liquid chromatography (HPLC).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: THE JOURNAL OF JAPAN SOCIETY FOR LASER SURGERY AND MEDICINE
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
