661: Pain associated with chorionic villus sampling--transabdominal versus transcervical approach

Abstract

ObjectiveTo compare anticipated and perceived pain associated with transabdominal (TA) and transcervical (TC) chorionic villus sampling (CVS).Study DesignWomen with singleton pregnancies undergoing CVS at one of two institutions from 04/01/2006 −06/30/2008 completed a pre-procedure 0-10 visual analog scale (VAS) (0=no pain, 10=excruciating pain) for anticipated TA and TC CVS-related pain. The sampling route was sonographically selected for ease of placental access. After the procedure, patients completed a VAS for perceived pain.Results121 women underwent TA (n=98) or TC (n=23) CVS at 11.9 ± 1.0 weeks for maternal age ≥35 years (n=82), abnormal aneuploidy screening (n=29), prior affected offspring (n=9), or other indications (n=19). Anticipated pain, 4.5 ± 2.0, was similar in patients ultimately having TA (4.6 ± 3.8) or TC (4.1 ± 2.2) CVS. Post-procedure perceived pain was significantly greater for TA (4.0 ± 2.4) than TC (2.6 ± 2.2) CVS, p=.01.ConclusionPerceived procedural pain is significantly greater for TA compared to TC CVS. These quantitative data are valuable for pre-procedure patient counseling and designing interventional analgesic studies. ObjectiveTo compare anticipated and perceived pain associated with transabdominal (TA) and transcervical (TC) chorionic villus sampling (CVS). To compare anticipated and perceived pain associated with transabdominal (TA) and transcervical (TC) chorionic villus sampling (CVS). Study DesignWomen with singleton pregnancies undergoing CVS at one of two institutions from 04/01/2006 −06/30/2008 completed a pre-procedure 0-10 visual analog scale (VAS) (0=no pain, 10=excruciating pain) for anticipated TA and TC CVS-related pain. The sampling route was sonographically selected for ease of placental access. After the procedure, patients completed a VAS for perceived pain. Women with singleton pregnancies undergoing CVS at one of two institutions from 04/01/2006 −06/30/2008 completed a pre-procedure 0-10 visual analog scale (VAS) (0=no pain, 10=excruciating pain) for anticipated TA and TC CVS-related pain. The sampling route was sonographically selected for ease of placental access. After the procedure, patients completed a VAS for perceived pain. Results121 women underwent TA (n=98) or TC (n=23) CVS at 11.9 ± 1.0 weeks for maternal age ≥35 years (n=82), abnormal aneuploidy screening (n=29), prior affected offspring (n=9), or other indications (n=19). Anticipated pain, 4.5 ± 2.0, was similar in patients ultimately having TA (4.6 ± 3.8) or TC (4.1 ± 2.2) CVS. Post-procedure perceived pain was significantly greater for TA (4.0 ± 2.4) than TC (2.6 ± 2.2) CVS, p=.01. 121 women underwent TA (n=98) or TC (n=23) CVS at 11.9 ± 1.0 weeks for maternal age ≥35 years (n=82), abnormal aneuploidy screening (n=29), prior affected offspring (n=9), or other indications (n=19). Anticipated pain, 4.5 ± 2.0, was similar in patients ultimately having TA (4.6 ± 3.8) or TC (4.1 ± 2.2) CVS. Post-procedure perceived pain was significantly greater for TA (4.0 ± 2.4) than TC (2.6 ± 2.2) CVS, p=.01. ConclusionPerceived procedural pain is significantly greater for TA compared to TC CVS. These quantitative data are valuable for pre-procedure patient counseling and designing interventional analgesic studies. Perceived procedural pain is significantly greater for TA compared to TC CVS. These quantitative data are valuable for pre-procedure patient counseling and designing interventional analgesic studies.