Abstract

In November 2013, a delayed release (DR) tablet formulation of posaconazole was approved with improved absorption compared to suspension. There have not been studies demonstrating the appropriate dose for antifungal prophylaxis in lung transplant recipients (LTR). The current labeled dose for prophylaxis is 300mg daily. Our goal is to determine the most appropriate dose of posaconazole for prophylaxis in LTR and correlate serum concentrations with different dosing regimens.

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