635 ILLNESS INTRUSIVENESS RATING SCALE AND IMPACT OF EVENTS SCALE AS QUALITY OF CARE INSTRUMENTS IN BLADDER CANCER

Abstract

You have accessJournal of UrologyGeneral & Epidemiological Trends & Socioeconomics: Quality of Life1 Apr 2011635 ILLNESS INTRUSIVENESS RATING SCALE AND IMPACT OF EVENTS SCALE AS QUALITY OF CARE INSTRUMENTS IN BLADDER CANCER Guilherme Godoy, Shubhada Sansgiry, Gilad E. Amiel, Seth P. Lerner, and David Latini Guilherme GodoyGuilherme Godoy Houston, TX More articles by this author , Shubhada SansgiryShubhada Sansgiry Houston, TX More articles by this author , Gilad E. AmielGilad E. Amiel Houston, TX More articles by this author , Seth P. LernerSeth P. Lerner Houston, TX More articles by this author , and David LatiniDavid Latini Houston, TX More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2011.02.1511AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES It is critical that objective measures of success are developed to assess patient's well being and quality of life (QoL). The Illness Intrusiveness Rating Scale (IIRS) and the Impact of Event Scale (IES) have been used in chronic diseases and refers to both illness and treatment disruptions, and its impact in life activities. The objective of this study is to assess IIRS and IES correlation with other validated instruments. METHODS The study included patients with both non muscle-invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC). The self-assessed instruments included demographics, basic information about the cancer, IIRS, IES, Fear of Recurrence Scale (FORS) and EORTC-QLQ30. Higher scores on the IIRS, the IES, including IES-intrusive and IES-avoidance domains, and FORS indicated worse functioning, while higher score on EORTC-QLQ30 indicated higher health-related QoL. Pearson's correlations were calculated between IIRS, IES, EORTC-QLQ30 and FORS scores and individual domains overall and in the NMIBC subset of patients. Subset analysis on the MIBC patients will be reported in the future when this subset matures. RESULTS At the time of analysis, there were 135 patients enrolled in this program, 117 with NMIBC and 18 with MIBC. The mean age was 63.7 years (SD, 9.6), with 69.6% of male. Mean (SD) IIRS and IES scores for the whole group were 22.3 (20.0) and 19.2 (17.2), respectively. Mean (SD) IIRS scores for NMIBC and MIBC were 18.8 (17.4) and 45.6 (20.6), respectively (t-test p<0.001). Mean (SD) IES scores for NMIBC and MIBC were 16.9 (16.5) and 33.7 (14.8), respectively (t-test p=0.001). Overall IIRS correlated well with IES (0.64) and its domains, IES-intrusiveness (0.62) and IES-avoidance (0.57), (p<0.0001). IIRS also correlated with FORS (0.55, p<0.0001), and EORTC-QLQ-30, especially with the global health status (QL) domain (−0.58, p<0.0001) and the social function (SF) domain (−0.69, p<0.0001). The IES correlated well with FORS (0.61), and QLQ-30 emotional functioning (EF) (−0.66) but only moderately with QL (<>230.44), (p<0.0001). In the subset of patients with NMIBC, IIRS maintained a moderate correlation with FORS, QL, and SF, with coefficients of 0.51, −0.50, −0.57, respectively (p<0.0001). In NMIBC patients, IES also maintained its moderate correlation with QL (−0.39), and good correlation with FORS (0.62) and EF (−0.66), (p<0.0001). CONCLUSIONS IIRS and IES are correlated with other validated instruments, and should be used to objectively measure health outcomes in patients with bladder cancer, especially with NMIBC. © 2011 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 185Issue 4SApril 2011Page: e256-e257 Advertisement Copyright & Permissions© 2011 by American Urological Association Education and Research, Inc.MetricsAuthor Information Guilherme Godoy Houston, TX More articles by this author Shubhada Sansgiry Houston, TX More articles by this author Gilad E. Amiel Houston, TX More articles by this author Seth P. Lerner Houston, TX More articles by this author David Latini Houston, TX More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...