628P Infection-related hospitalization and overall survival with primary prophylaxis for febrile neutropenia in patients with diffuse large B-cell lymphoma treated with R-CHOP: A nationwide population-based study

Abstract

Febrile neutropenia (FN) and chemotherapy-induced neutropenia (CIN) are common conditions involving dose reduction or delayed chemotherapy in patients with diffuse large B-cell lymphoma (DLBCL). Owing to the lack of real-word data on the effectiveness of rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP)-based primary prophylaxis (PP) in literature, we aimed to investigate the effects of PP with R-CHOP on the incidence of FN/CIN-related hospitalizations, overall survival (OS), and length of hospital stay in DLBCL patients.