Abstract
The information on Se is inadequate with regard to the relative tissue distribution and the reversibility of accumulation after the cessation of exposure in sucking subjects after the administration of the Se to their lactating mothers. Two lactating rat dams (dam A and B) were provided sodium selenite in their drinking water at the concentration of 0 and 3 ppm, respectively. There were 15 experimental pups (B) and 13 pups in control group (A). Experiment was carried out during the first 6 weeks post partum. Third group (C) comprised of 6 pups who were separated from dam B and adopted by dam A after the first 3 weeks. Se concentrations (μg/gm tissue) follows (X±SD):Standard at experimental versus control:*=<0.05, **=<0.01 Se concentrations were higher in tissues of pups B, however, pups C showed a reversal yet with persistence of higher levels in hair (p<0.05). There appears to be a transfer and accumulation of Se in tissues of suckling pups which is reversible. Hair Se determinations may be useful for assessment of internal organ Se status in Se exposed suckling subjects.
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