Abstract

B SE3.3 b Experiences of COVID-19 patients' viscoelastometry testing and case reports Reger B., Schrick D., Molnar T., Tokes-Fuzesi M. Dept. of Laboratory Medicine, Dept. of Anaesthesiology and Intensive Therapy, University of Pecs, Pecs, Hungary COVID-19 is commonly associated with macro- and microvascular thrombosis and endotheliopathy. In terms of significance, we compared our results with CT scores and other laboratory parameters of patients, and the effect of certain diseases (e.g., diabetes, cardiovascular disease, kidney disease, hypertension) was examined on the outcome of COVID-19 disease. For patients who were not hospitalized (42% of all examined patients) the median data were: age: 60 years, paraprotein: 1.05 g/L, lambda: 8.02 mg/L, kappa: 9.7 mg/L. For hospitalized patients (the remaining 58%): median age: 66 years, paraprotein: 4.9 g/L, lambda: 18.8 mg/L, kappa: 48.85 mg/L. 42% of the latter group were administered to intensive care (paraprotein: 4.65 g/L, lambda: 16.85 mg/L, kappa: 48.85 mg/L). 16% of all patients died because of a relapse or their disease transformed to leukaemia or they were directly after transplantation. SY2.5-8 Lunch symposium - Roche Hungary LS4.1-3 B Poster Presentations b Poster section - Analytics PS1.1-8 Poster section - Analytics and Case reports PS2.1-7 Poster section - COVID 19 PS3.1-8 Poster section - Hematology PS4.1-8 B Author index b B PL.1 b The HUNGARIAN JENDRASSIK-award lecture Fifteen years of experience in medical laboratory accr... Liszt F. Department of Laboratory Medicine, University of Pecs, Pecs, Hungary One and key of the priorities in laboratory medicine is improvement of quality management system for patient safety. [Extracted from the article] Copyright of Clinical Chemistry & Laboratory Medicine is the property of De Gruyter and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Highlights

  • The increasing number of more-and-more specific laboratory tests results in their inappropriately frequent usage that can end-up in “overtreatment” of patients and enhancement of laboratory costs

  • Clinical information systems can provide a proper interface for physicians to handle predefined minimal retesting intervals (MRI) regulations

  • Routine application of MRI testing can reduce the number of required tests and diminish the costs of laboratory testing

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Summary

Introduction

The increasing number of more-and-more specific laboratory tests results in their inappropriately frequent usage that can end-up in “overtreatment” of patients and enhancement of laboratory costs. From an analytical point of view, the TT3 promises to be more reliable With all this in mind, we aimed to examine how the FT3 and TT3 results correlate with each other on two measurement systems. Conclusions: Our results support that, measured on both systems, the TT3 method is superior to FT3, so it is recommended to supplement the currently used algorithm with TT3 measurement. This could reduce the possibility of an inappropriate therapeutic decision. Endogenous substances, such as natural, poly-reactive antibodies, autoantibodies (heterophiles), or human anti-animal antibodies together with other unsuspected binding proteins that are unique to the individual, can interfere with the reaction

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