608 High short-term effectiveness of modulated dry bed training in adolescents and young adults with treatment-resistant enuresis

Abstract

INTRODUCTION & OBJECTIVES: Two percent of adolescents and young adults suffer from therapy-resistant enuresis, with considerable negative impact on self-esteem and relationships. We evaluated the effect of a Modulated Dry Bed Training (MDBT) in a previously therapyresistant group of adolescents with enuresis, provided by a specialized enuresis-centre. MATERIAL & METHODS: Descriptive, retrospective cohort study. Between January 2003 and July 2013, 907 patients were treated by MDBT: a 5-days/4-nights in-hospital group training consisting of enuresis-anamnesis, explanation, alarm treatment, day-time activities with the purpose of increasing self-esteem and group contact. Structured follow-up was performed by telephone contact. Patients data were collected from the medical files. At 6 weeks, 3 and 6 months success of treatment was determined using ICCS-definitions. Secondary measurements included use of medication after treatment. Sensitivity analyses were performed to control for missing values. Differences between the subgroups gender, age and degree of enuresis were tested by Chi-Square test. RESULTS: Patients were aged 11-42 years (median 15, IQR 3.5), 34% female. At baseline, 81% had non-monosymptomatic enuresis, 65% primary enuresis, and 46% frequent enuresis (≥4 days/week). After 6 weeks, 46% (CI95% 43-50) and 41% of patients had a full or partial response, respectively. After 6 months this accounted for 68% (CI95% 65-72) and 25%. Females more often had a full response than males in all time frames. CONCLUSIONS: MBDT appeared to be highly effective on short term in adolescents with therapy-resistant enuresis. (Table Presented).