Abstract
Background: Neoadjuvant therapy followed by surgery is the current recommended treatment for esophageal cancer. However, there is controversy over the extent of lymphadenectomy in patients with near complete response to neoadjuvant chemoradiotherapy. Hence, this prospective study was performed to determine the feasibility, short-term outcomes and significance of thoracoscopic esophagectomy with total mediastinal lymphadenectomy in patients with near complete response to neoadjuvant chemoradiotherapy.
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