Abstract
Adult skin wounds are frequently accompanied by scar formation that can become fibrotic. Development of more efficient skin wound treatments is an urgent need. A fascinating and unique property of oral mucosa is that it rarely scars in response to wound healing, yet the mechanisms of scarless healing and fibroblast heterogeneity are yet to be revealed. The current project aims to enhance skin wound healing by disclosing oral mucosal fibroblast regenerative potential. Analysis of several timepoints of murine tongue wound healing by immunofluorescence and flow cytometry using markers of inflammation, proliferation and tissue remodelling revealed oral wound healing dynamics.
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