Abstract
sensitive responses to electrical field stimulation (EFS). Conclusion: This is the first demonstration of a bioengineered innervated human pyloric sphincter. Bioengineered pyloric sphincters maintained appropriate myogenic and neurogenic functionality. These bioengineered tissues have the potential for use as (1) functional replacement organs and (2) physiologically relevant models to investigate human pyloric sphincter disorders. This work was supported by Army, Navy, NIH, Air Force, VA and Health Affairs to support the AFIRM II effort, under Award No. W81XWH-13-2-0052; GU 7 and Wake Forest School of Medicine Internal Funds.
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