Abstract
Perfusion in vitro of human placenta with radioactive oestradiol-17β or oestrone led to the formation of a fraction more ‘polar’ than the starting material. In this fraction 6α-hydroxyoestradiol-17β has been identified by paperchromatography in various systems and by microchemical reactions as a major component. The same compound was also found after perfusion of 4- 14C-testosterone, 4- 14C-dehydro-epi-androsterone and 6,7- 3H-dehydro-epi-androsterone-sulphate.
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