Abstract
In the title compound, C23H26BrClN6, the imidazo[4,5-b]pyridine ring system (r.m.s. deviation = 0.012 Å) is inclined at angles of 19.37 (12) and 89.27 (13)° to the phenyl and triazole rings, respectively, while the phenyl and triazole rings subtend a dihedral angle of 71.23 (15)°. In the crystal, the molecules are linked by C—H...NI and bifurcated C—H...(NT,NT) (I = imidazo[4,5-b]pyridine and T = triazole) hydrogen bonds into a double-column structure propagating along the b-axis direction.
Highlights
In the title compound, C23H26BrClN6, the imidazo[4,5-b]pyridine ring system (r.m.s. deviation = 0.012 A ) is inclined at angles of 19.37 (12) and 89.27 (13) to the phenyl and triazole rings, respectively, while the phenyl and triazole rings subtend a dihedral angle of 71.23 (15)
The molecules are linked by C—HÁ Á ÁNI and bifurcated C—HÁ Á Á(NT,NT) (I = imidazo[4,5-b]pyridine and T = triazole) hydrogen bonds into a double-column structure propagating along the b-axis direction
As a continuation of our studies in this area (Bourichi et al, 2016), we report the synthesis and structure of the title compound (Fig. 1)
Summary
Some imidazopyridine derivatives have a significant inhibitory effect on target enzymes (Palmer et al, 2007; Katritzky et al, 2003). The most popular synthetic approach to these compounds involves the cyclo-condensation of 2,3-pyridinediamine with carboxylic acid derivatives or with aldehydes (Dubey et al, 2004). As a continuation of our studies in this area (Bourichi et al, 2016), we report the synthesis and structure of the title compound (Fig. 1). The imidazo[4,5-b]pyridine unit is planar to within 0.026 (5) A (for atom C7), and the r.m.s. deviation of the fitted atoms is 0.012 A. It is inclined by 19.37 (12) and 89.27 (13) to the phenyl and triazole rings, respectively, while phenyl and triazole rings are oriented at a dihedral angle of 71.23 (15).
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