Abstract
Underlying pathophysiological mechanisms of appetite and weight loss or decreased rate of weight gain related with psychostimulants for the treatment of ADHD have not been fully clarified yet. Nesfatin-1, discovered in recent years, released by mainly hypothalamus, is a peptide responsible for the appetite regulation, weight loss and metabolic regulation. We aimed to investigate whether there is an association between nesfatin-1 and etiopathogenesis of ADHD, treatment response and metabolic side effects of MPH by comparing pre-and post-treatment serum levels of Nesfatin-1 in prepubertal boys with ADHD.
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