Abstract
ICD-9 codes were used to identify obstetrical deliveries occurring calendar year 2005-2009, collated by screening culture result. All cases with positive culture results were subjected to medical record review to collect data on antibiotic sensitivity testing and population demographics. RESULTS: 20,042 obstetrical deliveries occurred during the five-year period under study. Carrier prevalence was 23.6% (n 4,738). Antibiotic sensitivity results were available for 812 isolates. 51.6% of isolates were universally-sensitive to penicillin, clindamycin, erythromycin and vancomycin. Individual antibiotic resistance prevalence rates were 3.7%, 25.2%, 46.4% and 0.0% respectively. Of those with penicillin resistance, 66.7% were also to resistant to clindamycin and erthyromycin. CONCLUSION: We report a regional subset of GBS isolates with penicillin resistance, and an increased rate of resistance to erythromycin comparative to other published reports. This may be due to established recommendations for antibiotic use, and/or actual antibiotic practice. The clinical implications of penicillin-resistance is unknown and further study is necessary to draw additional conclusions.
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