#5764 STUDY OF THE INFLUENCE OF PHYSICAL ACTIVITY ON THE FUNCTION OF EXTERNAL RESPIRATION IN PATIENTS WITH CKD IN THE PROCESS OF REHABILITATION

Abstract

Abstract Background and Aims Chronic kidney disease is a global health problem in which patients performance decreases as renal dysfunction progresses. The aim was to study of the function of external respiration in patients with CKD in the dynamics of a 12-week rehabilitation program. Method The study included 130 patients with CKD stages 2-3, aged 45 to 65 years, whose average age was 58.7 ± 0.73 years, and the proportion of women in the sample was 47.7%. All patients were examined of urea, serum creatinine, hemoglobin level. To determine exercise tolerance, a cardiorespiratory exercise test and spirogram were performed. Patients of the main group, depending on the initial CRET parameters, were divided into 2 subgroups: 1 subgroup - 67 patients who performed light intensity exercises; 2 subgroups - 33 patients who performed medium-intensity exercises for 12 weeks 3 times a week. The choice of training intensity was made according to the level of individual or subjective perception of the load and was calculated using the approximate heart rate. The control group consisted of patients with CKD stages 2-3 who did not perform physical training. Results An analysis of the spinographic parameters of patients with CKD revealed that the FEV1 and FVC indicators are of great importance in assessing the results of rehabilitation measures. There were positive results of 12 weeks of physical training with a more pronounced increase in FEV1. Patients in the light intensity training group achieved 35-45% of maximum heart rate or 40% of peakO2 consumption, and in the moderate intensity training group, 45-55% of maximum heart rate and 50-60% of peakO2 were achieved. The index (FEV1/FVC, in %) showed significant differences both in the initial indicators and in the dynamics. Conclusion In patients with pre-dialysis stages of CKD, a significant effect was revealed with the combined use of standard therapy and physical activity of light and moderate intensity, which ensures the preservation of positive dynamics in terms of the degree of increase in diastolic blood pressure at the time of exercise and respiratory parameters (FEV-1 and FVC, p<0.05).