Abstract
Skin replacement is of major concern especially for burnt people and giant nevi. According to our knowledge in modelling pigmented skin, we decided to develop an artificial, pigmented autologous skin for therapeutic use. Our pigmented models were made on dead deepidermized dermis, which do not allow standardization of procedure. Thus, since dermal collagen-based matrices such as IntegraTM or Matriderm® were used as dermal substitute from many years in reconstructive surgery, we decided to develop our artificial skin on these matrices.
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