Abstract
The treatment for patients with advanced stages esophagal carcinoma should be aimed at maintenance of local control by means of saving esophageal passage, improving disphagia and oral nutrition and preventing aspiration pnamonia as these sorts of complications are fatal. In this study, it was performed 15–16 Gy high dose rate intraluminal brachytherapy in 3 fraction preceded by 46–48 Gy external radiotherapy to 14 advanced stage inoperable patient in order not to exceed tolerable doses of the neighbouring tissues while maintaining efficient local control by radiation. Seven patients received neoadjuan chemotherapy. Patients were assessed symptomatically, endoscopically and radiologically every 3 months after completion of treatment. Before treatment 6 patients could not take and 8 patients received only fluid food. We achieved symptomatic palliation in all of the patients. Endoscopically it was founded no macroscobic tumor in 6 patients, 1–2 cm tumor in 4 patients and bigger than 2 cm in 4 patients 3 months after treatment. Seven patients had distant metastasis. Survival was between 5–18 (mean 10 months). We did not observe radiation ulcer. External radiotherapy plus intraluminal brachytherapy is effective and safe for obtaining local control in advanced disease esophagal carcinoma.
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